Release notes: HX Express v3 is an update to previous versions. The new features are centered around binomial fitting and handling of bimodal HDX-MS data. See tutorial videos for more information. Tested on PC versions of Office 2016 and 365 (not tested on Mac) The software is provided with some example data to test the functions within Excel. ‘Angiotensin_Bimodals’ and ‘GluFib_Bimodals’ are data sets of mixtures of differently deuterated peptides. The times correspond to the following mixtures of deuteration states: Time (min), mixture, deuteration % un - 0 TD - 100 1 - 25 2 - 50 3 - 75 4 1:1 0, 100 5 1:1 0, 25 6 1:1 0, 50 7 1:1 0, 75 8 1:1 25, 100 9 1:1 25, 50 10 1:1 25, 75 11 1:1 50, 100 12 1:1 50, 75 13 1:1 75, 100 14 1:3 25, 100 15 1:3 25, 50 16 1:3 25, 75 17 3:1 25, 75 18 3:1 75, 100 19 1:1:1 0, 25, 75 20 1:1:1 0, 50, 100 21 1:1:1 25,75,100 Angiotensin sequence: DRVYIHPF (2+) GluFib sequence: EGVNDNEEGFFSAR (2+) Pulse labeling example data is from peptide LTMGAKGFIGST (2+). All time points correspond to the folding times prior to the deuterium pulse. Please report bugs to Mike Guttman: mguttman@uw.edu