INTEREST GROUP
Hydrogen Exchange and Covalent Labeling
   
   
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18.June.2009

     
   
 
ASMS 2009, Philadelphia

 
Interest Group Meeting for 2008
 
Our interest group met Tuesday, June 2 at 5:45-8:00pm in Room 108A.
 

Probing protein conformation - What's new?

H/D Exchange & Covalent Labeling Interest Group

John R. Engen and Robert L. Hettich. presiding

The latest innovations in labeling strategies for understanding protein conformation and interactions will be discussed.  Several hot topics in both H/D exchange and covalent labeling will be covered.  The meeting will conclude with a software "free-for-all" where recent advances, challenges and solutions will be shown and explored.

 
Download the presentations:
 

   Hydrogen exchange
     SUPREX & SPROX: Where Do They Fit In The H/D Exchange & Covalent Labeling Landscape
       Graham West, Duke
     Interrogating Chromatin Structure and Dynamics with H/D Exchange Coupled to MS

       Ben Black, University of Pennsylvania School of Medicine

   Covalent labeling
     Protein Structure Determination by Combining Structural Mass Spectrometry Data with Rosetta

       Xiaojing Zheng, Case Western Reserve University

     Protein Hydroxyl Radical Labeling: Pitfalls and Opportunities

       Lars Konermann, University of Western Ontario

 
 

Software forum:
Participants:  Andrew Percy (Hydra), Bruce Pascal (HD Desktop), Paul Gershon (TOF2H),
                    Xinghua Lou (Hexicon), Magnus Palmblad (AutoHD2), David Weis (HX-Express)
 

Direct all inquiries to Bruce Pascal, Scripps Florida:
  

 
 

Meeting documents:
       Agenda        Oral and poster session summary

     Summary of meeting - Sent to ASMS on 06/19/2009 (on Proceedings DVD)

     Feedback to ASMS for 2010 meeting in Salt Lake City (coming soon)

   
   
 
  Other information from the meeting:
The short course at the 2009 meeting was well received.  Based on surveys and input from the ASMS Board the course may be offered at the 2010 meeting.  Stay tuned for further information. 
   
   
 
  Sessions at the 2009 conference that were of interest to our group:

A number of the oral session we requested have been approved and scheduled for the 2009 meeting.

We proposed the sessions below. The ones that were scheduled are in blue (7% of the meeting).
   
   Characterizing Protein-Ligand Interactions with Mass Spectrometry - TUES AM
   Hydrogen / deuterium exchange for protein structure and folding - TUES PM

   Combined labeling techniques for probing biomolecular structure
   MS and structural biology: combining 3D modeling with labeling
   Mass spectrometry in chemical biology - THURS AM
   Emerging MS methods for analysis of biopharmaceuticals - THURS PM
   
   
  Additional oral sessions on the program that are of interest to the group: 
   
  
Characterizing Protein-Protein Interactions - MON AM
   Tandem MS of Whole Proteins and Protein Complexes - MON PM
   Characterization of Membrane Proteins - WED PM

 

   
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