is Microsoft Excel-based software for semi-automated analysis of
hydrogen exchange mass spectrometry data. Any data in (x,y) format
can be analyzed or spectral data can be directly imported from Waters
Masslynx software. Output is deuterium uptake curves and
This version is an upgrade to the original freely available code, and was written by Miklos
Guttman at the University of Washington. It is described in the following publication:
Guttman M., Weis, D.D., Engen, J.R. & Lee,
K. K. (2013). Analysis of overlapped and noisy
Hydrogen/Deuterium exchange data.
Amer. Soc. Mass Spectrom. 24(12), 1906-1912.
HX-Express (version 1)
This is the original version, and was described in the publication:
Weis, D.D., Kass, I.J. & Engen, J.R. (2006). Semi-automated
analysis of hydrogen exchange mass spectra using HX-Express.
Amer. Soc. Mass Spectrom.